E. coli effects can last a lifetime (2024)

E. coli effects can last a lifetime (1) When she was 10 years old, Brianne Kiner became the public face of one of the country’s worst outbreaks of food poisoning.

According to the LA Times report, Brianne suffered from hemolytic uremic syndrome, or HUS, the most dreaded consequence of E. coli O157:H7 infection and the most common cause of kidney failure in children under 18. Of the 171 cases identified so far in the current spinach-related outbreak, 27 have been diagnosed with HUS. One person has died. Two other deaths are under investigation.

The death rate from HUS is 3% to 5%, doctors say. Ten percent of patients survive but have long-term kidney damage and may eventually require dialysis or a transplant. Brianne’s case was so severe that just about everyone expected her to die. She was the last to leave the hospital among those stricken in the Jack-in-the Box outbreak that sickened hundreds and killed four.

During the months she was laid up, the toxin produced by the bacteria attacked her brain, kidneys and liver, putting her in a coma for 40 days. She suffered strokes and seizures. Her infected pancreas lost the ability to produce insulin, and she developed diabetes. Doctors removed part of her inflamed intestine.

The $15.6-million settlement the Kiners won in 1995 from Jack-in-the-Box provides for Brianne’s support. She now lives on her own and takes community college classes part time – routine milestones for a 23-year-old, but they represent hard-won autonomy for someone stricken as severely as she was. Every three months, she visits her endocrinologist to check her diabetes, but she pronounces her health – and life – “Good.”

E. coli is commonly found in cow manure and passed to people though contaminated food. Most strains are ubiquitous and relatively harmless.

But somewhere along the way, E. coli O157:H7 evolved the ability to produce lethal toxins that can cross the intestinal wall and enter the bloodstream. The toxins flock to receptors in the kidneys, where they kill small blood vessels and clog waste filters. They can also harm the pancreas, liver and heart. Death is often a result of toxins infecting the brain and causing strokes or swelling. Sometimes, the damage reveals itself years later. Each kidney has about a million filters. On average, most people lose about 20% of these filters by the time they’re 80, just through wear and tear.

What saves the vast majority of children who fall ill from HUS is the resilience of the human body. Virtually nothing can be done to fight the infection once it is underway. Treatment consists of supporting the patient – from something as simple as hydration, all the way to dialysis – while the body fights off the toxins.

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E. coli effects can last a lifetime (2024)

FAQs

How long do the effects of E. coli last? ›

Symptoms usually last 5 to 10 days. People with mild symptoms usually recover on their own without treatment. Antibiotics are not helpful for treating E. coli O157 infections, and may even increase the likelihood of developing HUS.

Can E. coli cause lifelong problems? ›

coli effects can last a lifetime. When she was 10 years old, Brianne Kiner became the public face of one of the country's worst outbreaks of food poisoning. According to the LA Times report, Brianne suffered from hemolytic uremic syndrome, or HUS, the most dreaded consequence of E.

Does E. coli grow over time? ›

For example, E. coli can double every 20 min in the laboratory but we estimate that it only doubles every 15 h in the wild.

What does E. coli do to survive? ›

Pathogenic E. coli strains can survive in open environments. The ability to use nutrients and to attach to surfaces plays a crucial role in their survival in open environments. Escherichia coli O157:H7 is found in soil, manure, and irrigation water or contaminated seeds.

How long can E. coli live? ›

SURVIVAL OUTSIDE HOST: E. coli can survive for 1.5 hours to 16 months on dry inanimate surfaces 26.

How soon does E. coli affect you? ›

Symptoms of E. coli typically start appearing 3 to 4 days after eating or drinking something with the bacteria. However, symptoms can appear 1 to 10 days after you're exposed.

What is the most serious complication of E. coli? ›

coli (EHEC). STEC strains can cause serious illness in humans by producing toxins that can severely damage the lining of your intestines and kidneys. Infection with STEC strains can lead to serious complications like hemolytic uremic syndrome (HUS), which sometimes is fatal.

Can E. coli go away and come back? ›

Studies show that some E.coli might regrow even after chlorine treatment. You could also get E.coli drinking water from a private well, as the water may not have been disinfected before use.

Can E. coli affect your brain? ›

coli infections can have strokes and suffer permanent brain damage or death. In fact, in patients with E. coli infections, “brain involvement is the most frequent cause of fatalities.”1 Possible adverse events include seizures, stroke, coma, edema (swelling of the brain), and encephalopathy.

How long do bacteria live? ›

Bacteria divide somewhere between once every 12 minutes and once every 24 hours. So the average lifespan of a bacterium is around 12 hours or so. Read more: Are any bacteria visible to the naked eye?

Is E. coli helpful or harmful? ›

Yet despite all the attention given to their harmful brethren, most E. coli are not harmful to humans, and some are even beneficial. Many of us host a population of E. coli in our gut that aids digestion and protects us from other harmful microbes.

How is E. coli harmful? ›

Infections due to E. coli (Escherichia coli) bacteria can cause severe, bloody diarrhea. Sometimes they also cause urinary tract infections, pneumonia, meningitis, bacteremia (a bacterial infection in the blood), or sepsis (a dangerous full-body response to bacteremia).

What kills E. coli in the body? ›

Some antibiotics providers use to treat E. coli infections include: Trimethoprim/sulfamethoxazole (TMP/SMX).

What kills E. coli? ›

Thoroughly cooking meat, especially ground beef, can destroy E. coli bacteria. Ground beef should be cooked until it is no longer pink and juices run clear. When cooking hamburgers, the meat thermometer should read 160 degrees in the thickest part of the hamburger patty and the patty should not be pink inside.

How do you flush E. coli out of your system? ›

Treating E. Coli–Related Traveler's Diarrhea
  1. Stay hydrated. Consume plenty of fluids.
  2. Take antidiarrheal drugs. Use medication such as loperamide (Imodium), though people who have a fever or bloody stools should not take these, nor should children younger than 2 years.
  3. Ask if you need antibiotics.

How do you feel better after E. coli? ›

How can you care for yourself at home?
  1. E. coli usually goes away on its own. ...
  2. Do not use over-the-counter antidiarrheal medicine if you have diarrhea. ...
  3. When you feel like eating again, start with small amounts of food.
  4. To prevent dehydration, drink plenty of fluids.

Can E. coli lay dormant in the body? ›

Research has shown that E. coli can hide out in bladder cells for months after a UTI seems to have been cured, and then re-emerge to cause another infection.

What happens if you drink water with E. coli in it? ›

coli/ fecal coliform bacteria in the drinking water supply. E. coli and fecal coliform bacteria indicate that the water may be contaminated with human or animal wastes. Drinking water with these wastes can cause short-term illness, such as diarrhea, cramps, nausea, headaches, or other symptoms.

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